Abstract The ALPK3 gene encodes alpha-protein kinase 3. a cardiac pseudo-kinase of unknown function. Heterozygous truncating variants (ALPK3tv) can cause dominant adult-onset hypertrophic cardiomyopathy (HCM). Here we confirm an excess of ALPK3tv in sarcomere-gene negative HCM patients. https://storeanimalwiz.shop/product-category/litter-boxes/